Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm3.1Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
|
|
|
normal phenotype
|
• mice do not develop any renal or extra-renal defects even with aging
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2.2Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
Pkd1tm3.1Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
|
|
|
normal phenotype
|
• mice are viable and fertile and do not develop renal, hepatic, or pancreatic cysts by 18 months of age
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm3.1Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
Pkd1tm3.2Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
|
|
|
normal phenotype
|
• mice are viable and fertile and do not develop renal, hepatic, or pancreatic cysts by 18 months of age
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2.2Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
Pkd1tm3.1Bol mutation
(0 available);
any
Pkd1 mutation
(153 available)
Tg(Nes-cre)1Kln mutation
(4 available)
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Hydrocephalus in Pkd1tm2.2Bol/Pkd1tm3.1Bol Tg(Nes-cre)1Kln/0 mice
mortality/aging
nervous system
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• at P10, mice exhibit a triventricular phenotype unlike wild-type mice
|
renal/urinary system
growth/size/body