Phenotypes associated with this allele

• Allele Symbol: Psat1^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4363603
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psat1^tm1a(KOMP)Wtsi/Psat1^tm1a(KOMP)Wtsi	B6JTyr;B6N-Psat1^tm1a(KOMP)Wtsi/Wtsi	MGI:6263260
hm2	Psat1^tm1a(KOMP)Wtsi/Psat1^tm1a(KOMP)Wtsi	involves: C57BL/6N	MGI:5544031
ht3	Psat1^tm1a(KOMP)Wtsi/Psat1^+	B6JTyr;B6N-Psat1^tm1a(KOMP)Wtsi/Wtsi	MGI:5781712

Genotype
MGI:6263260

hm1

• Allelic Composition: Psat1^{tm1a(KOMP)Wtsi}/Psat1^{tm1a(KOMP)Wtsi}
• Genetic Background: B6JTyr;B6N-Psat1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0151_3_G04

Data Sources

IMPC Data for Psat1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

Genotype
MGI:5544031

hm2

• Allelic Composition: Psat1^{tm1a(KOMP)Wtsi}/Psat1^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0151_3_G04

craniofacial

abnormal craniofacial morphology ( J:200082 )

• in 6 of 7 mice at E14.5

growth/size/body

fetal growth retardation ( J:200082 )

• in 6 of 7 mice at E14.5

nervous system

exencephaly ( J:200082 )

• in 6 of 7 mice at E14.5

Genotype
MGI:5781712

ht3

• Allelic Composition: Psat1^{tm1a(KOMP)Wtsi}/Psat1⁺
• Genetic Background: B6JTyr;B6N-Psat1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0151_3_G04

Data Sources

IMPC Data for Psat1

growth/size/body

increased body weight ( J:175295 )

IMPC - WTSI

homeostasis/metabolism

decreased blood urea nitrogen level ( J:175295 )

IMPC - WTSI