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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Wnk4tm2.1Suc
targeted mutation 2.1, Shinichi Uchida
MGI:4360633
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Wnk4tm2.1Suc/Wnk4tm2.1Suc involves: 129S4/SvJae * C57BL/6 MGI:4360644


Genotype
MGI:4360644
hm1
Allelic
Composition
Wnk4tm2.1Suc/Wnk4tm2.1Suc
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnk4tm2.1Suc mutation (0 available); any Wnk4 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• when fed a low-potassium diet
• at days 5, 6, and 7 under a low-salt diet and during the transitional period from low- to high-salt diet, mice exhibit increased sodium excretion compared with similarly treated wild-type mice

cardiovascular system
• when fed a normal or low-salt diet, mice exhibit decreased systolic blood pressure during active periods compared with similarly treated wild-type mice

homeostasis/metabolism
• when fed a low-potassium diet
• at days 5, 6, and 7 under a low-salt diet and during the transitional period from low- to high-salt diet, mice exhibit increased sodium excretion compared with similarly treated wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory