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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lrrk2tm1Arte
targeted mutation 1, TaconicArtemis
MGI:4357791
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Lrrk2tm1Arte/Lrrk2tm1Arte involves: C57BL/6N MGI:4357792


Genotype
MGI:4357792
hm1
Allelic
Composition
Lrrk2tm1Arte/Lrrk2tm1Arte
Genetic
Background
involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrk2tm1Arte mutation (0 available); any Lrrk2 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• increased volume of the supra-pyramidal and intra-infra-pyramidal mossy fiber projections
• however, mice exhibit normal volume of Hilar mossy fibers
• increased dendritic length, branching and complexity of young immature neurons in the adult dentate gyrus
• DCX+ hippocampal neuroblasts in the adult dentate gyrus
• increased density of early and intermediate DCX+ neuroblasts in the adult dentate gyrus
• however, mice exhibit normal numbers of late neuroblasts





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory