• at P35 rod appear swollen and nonuniform in shape with expanded and constricted regions consistent with the elongated disks

• at P18 - P24 outer segments are shorter, often bent and less rigid compared to wild-type controls

• at P20 outer segments appear misaligned and abnormal elongation of the disks is seen

• at P60 outer segments contain elongated membranous material that most likely originates from the disks

• by 3 - 4 months of age rod outer segments are lost due to progressive degeneration

• complete loss of the photoreceptor layer by 1 year of age

• rods have smaller circulating currents and are less sensitive to light stimulation compared to wild-type controls

• unlike mice homozygous for Cngb1^tm1.1Biel, body weight is similar to controls (J:150504)

• at P35 rod appear swollen and nonuniform in shape with expanded and constricted regions consistent with the elongated disks

• at P18 - P24 outer segments are shorter, often bent and less rigid compared to wild-type controls

• at P20 outer segments appear misaligned and abnormal elongation of the disks is seen

• at P60 outer segments contain elongated membranous material that most likely originates from the disks

• by 3 - 4 months of age rod outer segments are lost due to progressive degeneration

• complete loss of the photoreceptor layer by 1 year of age