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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Foxp2tm2.2Woen
targeted mutation 2.2, Wolfgang Enard
MGI:3851108
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Foxp2tm2.2Woen/Foxp2+ involves: C57BL/6 * C57BL/6J MGI:3851148


Genotype
MGI:3851148
ht1
Allelic
Composition
Foxp2tm2.2Woen/Foxp2+
Genetic
Background
involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp2tm2.2Woen mutation (0 available); any Foxp2 mutation (52 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• on a modified hole board
• increased exploration of a novel object
• mice react less to a clicking sound than wild-type mice
• mice exhibit slightly impaired motor learning on a rotarod compared with wild-type mice

homeostasis/metabolism
• mice exhibit lower plasma inorganic phosphorus levels compared with wild-type mice
• mice exhibit a slightly higher plasma Ferritin levels compared with wild-type mice
• in the frontal cortex, cerebellum, caudate-putamen, nucleus accumbens, and globus pallidus
• mice assimilate more energy than wild-type mice
• increased in the frontal cortex, cerebellum, caudate-putamen, nucleus accumbens, and globus pallidus

respiratory system
• mice exhibit higher respiratory rate during activity and at rest compared with wild-type mice

immune system

adipose tissue

cardiovascular system
• mice exhibit a lower pulse rate than wild-type mice

growth/size/body

hematopoietic system





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory