All Phenotypes Dkc1<tm2Pjma> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dkc1^tm2Pjma
targeted mutation 2, Philip J Mason
MGI:3849598

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Dkc1^tm2Pjma/Y	chimera involves: 129X1/SvJ * C57BL/6J	MGI:3849602

Allelic Composition	Dkc1^tm2Pjma/Y
Genetic Background	chimera involves: 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dkc1^tm2Pjma mutation (0 available); any Dkc1 mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal fertility/fecundity ( J:149894 )

• despite detection of cells carrying the mutant allele in the testes no pups carrying the mutant allele are produced; normal litter sizes suggest that there is no germ line transmission of this allele

cellular

abnormal cell physiology ( J:149894 )

• contribution of mutant ES cells to tissues is lower than coat color would suggest it should be

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	dyskeratosis congenita	DOID:2729	OMIM:PS127550	J:149894

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23