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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Pcp2-FMR1*)1Dln
transgene insertion 1, David L Nelson
MGI:3848937
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Pcp2-FMR1*)1Dln/0 C57BL/6-Tg(Pcp2-Fmr1*)1Dln MGI:3848946


Genotype
MGI:3848946
tg1
Allelic
Composition		 Tg(Pcp2-FMR1*)1Dln/0
Genetic
Background		 C57BL/6-Tg(Pcp2-Fmr1*)1Dln
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:149320 )
• compared to in mice expressing FMR1 without the 90 CGG repeats

nervous system
neuronal intranuclear inclusions ( J:149320 )
• Purkinje cells contain inclusions unlike in cells expressing FMR1 without the 90 CGG repeats
• Purkinje cell axons are swollen unlike in cells expressing FMR1 without the 90 CGG repeats

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
fragile X-associated tremor/ataxia syndrome DOID:0050879 OMIM:300623
 J:149320




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory