Mouse Genome Informatics
tg1
    Tg(Pcp2-FMR1*)1Dln/0
C57BL/6-Tg(Pcp2-Fmr1*)1Dln
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological
• compared to in mice expressing FMR1 without the 90 CGG repeats

nervous system
• Purkinje cells contain inclusions unlike in cells expressing FMR1 without the 90 CGG repeats
• Purkinje cell axons are swollen unlike in cells expressing FMR1 without the 90 CGG repeats

Mouse Models of Human Disease
OMIM IDRef(s)
Fragile X Tremor/Ataxia Syndrome; FXTAS 300623 J:149320