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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(FCER1A)1Bhk
transgene insertion 1, Beverly H Koller
MGI:3846551
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Fcer1atm1Knt/Fcer1atm1Knt
Tg(FCER1A)1Bhk/?
B6.129-Fcer1atm1Knt Tg(FCER1A)1Bhk MGI:3851203


Genotype
MGI:3851203
cx1
Allelic
Composition
Fcer1atm1Knt/Fcer1atm1Knt
Tg(FCER1A)1Bhk/?
Genetic
Background
B6.129-Fcer1atm1Knt Tg(FCER1A)1Bhk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcer1atm1Knt mutation (3 available); any Fcer1a mutation (13 available)
Tg(FCER1A)1Bhk mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls

hematopoietic system
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory