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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Zfp57tm1.1Xjli
targeted mutation 1.1, Xiajun Li
MGI:3826984
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Zfp57tm1.1Xjli/Zfp57tm1.1Xjli either: 129S6/SvEvTac-Zfp57tm1.1Xjli or (involves: 129S6/SvEvTac * Black Swiss * FVB/N) MGI:3826997


Genotype
MGI:3826997
hm1
Allelic
Composition
Zfp57tm1.1Xjli/Zfp57tm1.1Xjli
Genetic
Background
either: 129S6/SvEvTac-Zfp57tm1.1Xjli or (involves: 129S6/SvEvTac * Black Swiss * FVB/N)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp57tm1.1Xjli mutation (0 available); any Zfp57 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 80% of homozygous mice from homozygous females die between E14.5 and E16.5
• half as many mice as expected are alive at weaning
• no homozygous mice from homozygous females survive to weaning

cellular
• in homozygous mutant embryos derived from a null females
• 80% of homozygous mice from homozygous females die between E14.5 and E16.5
• no homozygous mice from homozygous females survive to weaning
• imprinting is abnormal in homozygous mutant embryos derived from a null females





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory