About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Glrxtm3Ysh
targeted mutation 3, Ye-Shih Ho
MGI:3820704
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Glrxtm3Ysh/Glrxtm3Ysh involves: 129S1/Sv * 129X1/SvJ MGI:3820709


Genotype
MGI:3820709
hm1
Allelic
Composition
Glrxtm3Ysh/Glrxtm3Ysh
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glrxtm3Ysh mutation (0 available); any Glrx mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• cells larger
• cells round rather than elongated

cellular
• reduced cell membrane integrity in lens epithelial cells in culture
• reduced viability of lens epithelial cells in culture
• lens epithelial cells in culture show slower migration
• doubling time for lens epithelial cells in culture is 33 hours compared to 13 hours for controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/04/2020
MGI 6.15
The Jackson Laboratory