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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Six3tm3Gco
targeted mutation 3, Guillermo Oliver
MGI:3814869
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Six3tm3Gco/Six3tm3Gco
Foxg1tm1(cre)Skm/Foxg1+
involves: 129S1/Sv * C57BL/6 MGI:3814903


Genotype
MGI:3814903
cn1
Allelic
Composition
Six3tm3Gco/Six3tm3Gco
Foxg1tm1(cre)Skm/Foxg1+
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1(cre)Skm mutation (2 available); any Foxg1 mutation (28 available)
Six3tm3Gco mutation (0 available); any Six3 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• many display a phenotype typical of holoprosencephaly
• anterior diencephalon is normal

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
holoprosencephaly 2 DOID:0110872 OMIM:157170
J:140315





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory