Mouse Genome Informatics
tg1
    Tg(MT1A-Dyrk1a)33Xest/0
involves: C57BL/6 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological
• mice exhibit learning in a Morris water maze compared to wild-type mice with longer escape latencies in the first acquisition sessions
• mice are not effective at discriminating previously trained quadrants
• in a repeated acquisition version of the Morris water maze, mice display increased escape latencies and distance traveled compared to wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Down Syndrome 190685 J:71821