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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(MT1A-Dyrk1a)33Xest
transgene insertion 33, Xavier Estivill
MGI:3814577
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(MT1A-Dyrk1a)33Xest/0 involves: C57BL/6 * SJL MGI:3814580


Genotype
MGI:3814580
tg1
Allelic
Composition
Tg(MT1A-Dyrk1a)33Xest/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit learning in a Morris water maze compared to wild-type mice with longer escape latencies in the first acquisition sessions
• mice are not effective at discriminating previously trained quadrants
• in a repeated acquisition version of the Morris water maze, mice display increased escape latencies and distance traveled compared to wild-type mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Down Syndrome 190685 J:71821





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory