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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Creb3l3tm1.1Sad
targeted mutation 1.1, Stephen A Duncan
MGI:3811836
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Creb3l3tm1.1Sad/Creb3l3tm1.1Sad involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:3811850


Genotype
MGI:3811850
hm1
Allelic
Composition
Creb3l3tm1.1Sad/Creb3l3tm1.1Sad
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Creb3l3tm1.1Sad mutation (1 available); any Creb3l3 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice fail to increase SAP levels in circulation 24 hours after injection with tunicamycin
• mice fail to increase serum amyloid P-component levels after injection with tunicamycin
• mRNAs of other acute phase proteins like C-reactive protein and serum amyloid A3 also fail to increase in the liver 24 hours after tunicamycin injection

homeostasis/metabolism
• mice fail to increase SAP levels in circulation 24 hours after injection with tunicamycin





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory