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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(THY1-SNCA*A53T)F53Sud
transgene insertion F53, Thomas C Sudhof
MGI:3811331
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(THY1-SNCA*A53T)F53Sud/0 involves: C57BL/6 MGI:3811387


Genotype
MGI:3811387
tg1
Allelic
Composition
Tg(THY1-SNCA*A53T)F53Sud/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(THY1-SNCA*A53T)F53Sud mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• resting tremor initially observed around 8 months of age
• initially observed around 8 months of age

nervous system
• cell death is seen in spinal cord and is extensive in brain
• results in hindlimb paralysis around 8 months of age

cellular
• cell death is seen in spinal cord and is extensive in brain





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory