Phenotypes associated with this allele

• Allele Symbol: Sox5^tm2.1Vlf
• Allele Name: targeted mutation 2.1, Veronique Lefebvre
• Allele ID: MGI:3799355
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sox5^tm2.1Vlf/Sox5^tm2.1Vlf	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL	MGI:3800350

Genotype
MGI:3800350

hm1

• Allelic Composition: Sox5^tm2.1Vlf/Sox5^tm2.1Vlf
• Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:137217 )

• die at birth

skeleton

abnormal sternum ossification ( J:137217 )

• irregularly mineralized

abnormal thoracic cage shape ( J:137217 )

• narrow thoracic cage

abnormal cervical vertebrae morphology ( J:137217 )

• delayed mineralization of cervical vertebral bodies

craniofacial

palatal shelves fail to meet at midline ( J:137217 )

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )

digestive/alimentary system

palatal shelves fail to meet at midline ( J:137217 )

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )

growth/size/body

palatal shelves fail to meet at midline ( J:137217 )

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )