Analysis Tools
mortality/aging
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• mice die at E9.5
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embryo
growth/size/body
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Allele Symbol Allele Name Allele ID |
Ankrd11Yod yoda MGI:3797584 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die at E9.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• incomplete closure
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• mice exhibit decreased interdigitation of the frontonasal suture compared to in wild-type mice
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• increased in length
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• the nasal bone morphology is altered such that the skull has a domed shape
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• the periosteal perimeter is decreased in female but not male mice compared to wild-type mice
• the enodosteal perimeter and medullary areas are decreased in male and female mice compared to wild-type mice
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• in female but not male mice
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• at 3 months of age, bone mineral density is decreased 5.5% in the femora compared to in wild-type femora
• at 7 months of age, bone mineral density is decreased 27% in the femora compared to in wild-type femora
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• cortical bone area is decreased in female but not male mice compared to wild-type mice
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• mice exhibit loss of bone mass that is more severe in female mice
• however, cancellous bone mass is normal
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• the nasal bone morphology is altered such that the skull has a domed shape
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• mice exhibit shorter and wider faces than wild-type mice
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• mice exhibit shorter and wider faces than wild-type mice
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• at weaning and persisting through the rest of their lives
• however, lean and fat mass are normal
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• at weaning mice are shorter in length than wild-type mice and at 6 months mice are 9% shorter in length than wild-type mice
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• in female but not male mice
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• incomplete closure
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• mice exhibit decreased interdigitation of the frontonasal suture compared to in wild-type mice
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• increased in length
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• the nasal bone morphology is altered such that the skull has a domed shape
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• mice exhibit shorter and wider faces than wild-type mice
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• mice exhibit shorter and wider faces than wild-type mice
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• in female but not male mice
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• the nasal bone morphology is altered such that the skull has a domed shape
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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