All Phenotypes Abca4<tm1Kpal> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Abca4^tm1Kpal
targeted mutation 1, Krzysztof Palczewski
MGI:3793964

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Abca4^tm1Kpal/Abca4^tm1Kpal Rdh8^tm1Kpal/Rdh8^tm1Kpal	involves: 129	MGI:6159294

Allelic Composition	Abca4^tm1Kpal/Abca4^tm1Kpal Rdh8^tm1Kpal/Rdh8^tm1Kpal
Genetic Background	involves: 129

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca4^tm1Kpal mutation (0 available); any Abca4 mutation (107 available)
Rdh8^tm1Kpal mutation (2 available); any Rdh8 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal eye morphology ( J:213619 )

• the eyecups of 6 month old mice contain the fluorescent by-product of retinal metabolism lipofusin pdA2E

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
age related macular degeneration	DOID:10871	OMIM:PS603075	J:213619
Stargardt disease	DOID:0050817	OMIM:248200 OMIM:600110 OMIM:603786	J:213619

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23