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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Igh-3/Igh-6VD93)1241Ust
transgene insertion 1241 Ursula Storb
MGI:3793439
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Igh-3/Igh-6VD93)1241Ust/? C57BL/6-Tg(Igh-3/Igh-6VD93)1241Ust MGI:3798822


Genotype
MGI:3798822
tg1
Allelic
Composition
Tg(Igh-3/Igh-6VD93)1241Ust/?
Genetic
Background
C57BL/6-Tg(Igh-3/Igh-6VD93)1241Ust
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Igh-3/Igh-6VD93)1241Ust mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• splenic B cells co-express gamma 2b (Igh-3) and mu (Igh-6) on all Igh-3+ cells
• less than 1% of splenic lymphocytes are either mu or kappa positive in 2 week old mice
• by 4 weeks of age, mice exhibit approximately 3 fold fewer mu or kappa positive splenic B cells

hematopoietic system
• splenic B cells co-express gamma 2b (Igh-3) and mu (Igh-6) on all Igh-3+ cells
• less than 1% of splenic lymphocytes are either mu or kappa positive in 2 week old mice
• by 4 weeks of age, mice exhibit approximately 3 fold fewer mu or kappa positive splenic B cells





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory