Mouse Genome Informatics
cn1
    Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Tlx3tm1(cre)Qima/Tlx3+

involves: 129/Sv
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological
N
• mice do not show skin lesions or heightened itch responses to pruritic agents (J:158273)

integument
N
• mice do not show skin lesions in response to selective deletion in excitatory neurons in dorsal horn (J:158273)


Mouse Genome Informatics
cn2
    Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc
Tlx3tm1(cre)Qima/Tlx3+

involves: 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
• mice survive 102 days

tumorigenesis
• 40% of mice develop focal medulloblastomas and have a mean survival of 102 days

Mouse Models of Human Disease
OMIM IDRef(s)
Medulloblastoma; MDB 155255 J:139574