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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Flvcr1tm1Jlab
targeted mutation 1, Janis L Abkowitz
MGI:3776021
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Flvcr1tm1Jlab/Flvcr1tm1Jlab
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA MGI:3807529


Genotype
MGI:3807529
cn1
Allelic
Composition
Flvcr1tm1Jlab/Flvcr1tm1Jlab
Tg(Mx1-cre)1Cgn/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flvcr1tm1Jlab mutation (0 available); any Flvcr1 mutation (30 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some intrauterine deaths occur between E14.5 and E16.5, but on a congenic background, some homozygous embryos surviving past E7.5 die at E12.5
• some intrauterine deaths occur at or before E7.5

limbs/digits/tail
• Background Sensitivity: at E14.5, limb maturation, hand, and digit maturation are abnormal; more apparent at time of death than on a congenic background
• at E14.5, digit maturation is abnormal

craniofacial
• Background Sensitivity: more obvious at time of death on mixed background versus congenic

renal/urinary system
N
• genitourinary system appears grossly normal at E14.5

reproductive system
N
• genitourinary system appears grossly normal at E14.5

respiratory system
N
• pulmonary system appears grossly normal at E14.5

cardiovascular system
N
• cardiovascular system appears grossly normal at E14.5

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Diamond-Blackfan anemia DOID:1339 OMIM:PS105650
J:132057





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory