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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nlgn4lGt(XST093)Byg
gene trap XST093, BayGenomics
MGI:3775814
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nlgn4lGt(XST093)Byg/Nlgn4lGt(XST093)Byg B6.129P2-Nlgn4xGt(XST093)Byg MGI:3783593


Genotype
MGI:3783593
hm1
Allelic
Composition
Nlgn4lGt(XST093)Byg/Nlgn4lGt(XST093)Byg
Genetic
Background
B6.129P2-Nlgn4xGt(XST093)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlgn4lGt(XST093)Byg mutation (1 available); any Nlgn4l mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• attack latencies and frequency to an unfamiliar intruder mouse in the resident were reduced
• mutant mice spent 45% less time in direct contact with each other than wild-type control in an open arena
• no social preference to investigate unfamiliar mouse
• the latency to start calling and frequency of calls by male mice upon contact with a female mouse in estrous were reduced

nervous system
• small but significant reductions in the volume of the total brain and brainstem

Mouse Models of Human Disease
OMIM ID Ref(s)
Autism 209850 J:131843





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory