Analysis Tools
homeostasis/metabolism
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• similar to the decrease in Phexhyp hemizygous male mice at 8 weeks of age
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• reduction in renal phosphate uptake at 8 weeks of age is similar to that in Phexhyp hemizygous male mice
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renal/urinary system
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• reduction in renal phosphate uptake at 8 weeks of age is similar to that in Phexhyp hemizygous male mice
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skeleton
short femur
(
J:131043
)
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• the inner lacunocanalicular wall is buckled and enlarged
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• osteocyte lacunae are increased in size and randomly organized compared to those in control bone
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osteomalacia
(
J:131043
)
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• osteomalacia characterized by hyperosteoidosis and an excess of unmineralilized osteoid
• severity of osteomalacia is similar to that of Phexhyp hemizygous male mice
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limbs/digits/tail
short femur
(
J:131043
)
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