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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map1lc3btm1Mrab
targeted mutation 1, Marlene Rabinovtich
MGI:3774111
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Map1lc3btm1Mrab/Map1lc3btm1Mrab involves: 129P2/OlaHsd MGI:3776503


Genotype
MGI:3776503
hm1
Allelic
Composition		 Map1lc3btm1Mrab/Map1lc3btm1Mrab
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map1lc3btm1Mrab mutation (1 available); any Map1lc3b mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:130322 )
N
• mice exhibit normal longevity
decreased susceptibility to induced morbidity/mortality ( J:130322 )
• in the absence of feeding, neonates survive longer than wild-type mice

reproductive system
reproductive system phenotype ( J:130322 )
N
• mice breed normally

digestive/alimentary system
abnormal intestinal goblet cell morphology ( J:206181 )
• goblet cells exhibit increased mucin accumulation compared with control cells

cellular
abnormal intestinal goblet cell morphology ( J:206181 )
• goblet cells exhibit increased mucin accumulation compared with control cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory