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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sphk1tm1Npa
targeted mutation 1, Novartis Pharma AG
MGI:3769485
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sphk1tm1Npa/Sphk1tm1Npa BALB/c-Sphk1tm1Npa MGI:3769495


Genotype
MGI:3769495
hm1
Allelic
Composition
Sphk1tm1Npa/Sphk1tm1Npa
Genetic
Background
BALB/c-Sphk1tm1Npa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sphk1tm1Npa mutation (0 available); any Sphk1 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• when treated with 1mg/kg FTY720, mice exhibit a 75% reduction in peripheral lymphocytes compared to wild-type mice

hematopoietic system
• when treated with 1mg/kg FTY720, mice exhibit a 75% reduction in peripheral lymphocytes compared to wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory