immune system
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• following injection of IL-1beta into the peritoneum to induce peritonitis, total leukocyte count is increased and there is a 3-fold increase in the percent of neutrophils that migrate into the peritoneal cavity compared to wild-type mice
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• 30 minutes after stimulation with LPS leukocytes accumulate in the vessels and airways in the lungs unlike in wild-type mice
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• following injection of IL-1beta into the peritoneum to induce peritonitis, the number of migrating neutrophils is increased 6-fold (2.44x106+/-1x106 compared to 0.382x106+/-0.124x106 in wild-type mice)
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• following injection of IL-1beta, leukocyte transmigration is increased 2-fold compared to in wild-type mice
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• following injection of IL-1beta, leukocyte adhesion is increased 2-fold compared to in wild-type mice
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• following intranasal LPS challenge, the number of granulocytes is increased by 4-fol and the number of inflammatory monocytes is increased by 2-fold in bronchoalveolar lavage fluid
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respiratory system
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• following intranasal LPS challenge, the number of granulocytes is increased by 4-fol and the number of inflammatory monocytes is increased by 2-fold in bronchoalveolar lavage fluid
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digestive/alimentary system
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• following injection of IL-1beta into the peritoneum to induce peritonitis, total leukocyte count is increased and there is a 3-fold increase in the percent of neutrophils that migrate into the peritoneal cavity compared to wild-type mice
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cellular
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• following injection of IL-1beta into the peritoneum to induce peritonitis, the number of migrating neutrophils is increased 6-fold (2.44x106+/-1x106 compared to 0.382x106+/-0.124x106 in wild-type mice)
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• following injection of IL-1beta, leukocyte transmigration is increased 2-fold compared to in wild-type mice
|
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• following injection of IL-1beta, leukocyte adhesion is increased 2-fold compared to in wild-type mice
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hematopoietic system
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• 30 minutes after stimulation with LPS leukocytes accumulate in the vessels and airways in the lungs unlike in wild-type mice
|
|
• following injection of IL-1beta into the peritoneum to induce peritonitis, the number of migrating neutrophils is increased 6-fold (2.44x106+/-1x106 compared to 0.382x106+/-0.124x106 in wild-type mice)
|
|
• following injection of IL-1beta, leukocyte transmigration is increased 2-fold compared to in wild-type mice
|
|
• following injection of IL-1beta, leukocyte adhesion is increased 2-fold compared to in wild-type mice
|