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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
sbse
small body and small ear
MGI:3758823
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
sbse/sbse C57BL/6J-sbse/GrsrJ MGI:3767240


Genotype
MGI:3767240
hm1
Allelic
Composition
sbse/sbse
Genetic
Background
C57BL/6J-sbse/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
sbse mutation (1 available); any sbse mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial

skeleton
• whole body bone mineral content is decreased
• whole body bone mineral density is decreased

growth/size/body
• weight of homozygotes at ages 4, 8, 12, and 16 weeks is approximately 70% that of heterozygous controls

hearing/vestibular/ear
• at 7 weeks of age homozygotes have an ABR threshold about 20 db higher than controls, and at 3 months of age it is 30 db higher

reproductive system
• homozygous females bred with heterozygous males have an average litter size of 4.3 pups, while heterozygous females bred with heterozygous or homozygous males have an average litter size of 5.4 pups

nervous system

adipose tissue
• PIXImus densitometry shows decreased whole body fat

endocrine/exocrine glands
N
• pituitary assessment found no abnormalities

vision/eye
N
• eyes are normal by ophthalmoscopic examination at 4 weeks of age





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory