Mouse Genome Informatics
cn1
     Nr5a2tm1Sjns/Nr5a2tm1Sjns
Tg(Vil-cre/ERT2)23Syr/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
digestive/alimentary system
colonic necrosis ( J:123697 )
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis results in severe lesions with advanced necrosis
increased susceptibility to induced colitis ( J:123697 )
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis is more severe than in wild-type mice

immune system
increased susceptibility to induced colitis ( J:123697 )
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis is more severe than in wild-type mice