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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nr5a2tm1Sjns
targeted mutation 1, Kristina Schoonjans
MGI:3720193
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Nr5a2tm1Sjns/Nr5a2tm1Sjns
Tg(Vil-cre/ERT2)23Syr/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL MGI:3721528


Genotype
MGI:3721528
cn1
Allelic
Composition
Nr5a2tm1Sjns/Nr5a2tm1Sjns
Tg(Vil-cre/ERT2)23Syr/?
Genetic
Background
involves: 129/Sv * C57BL/6 * DBA/2 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr5a2tm1Sjns mutation (0 available); any Nr5a2 mutation (80 available)
Tg(Vil-cre/ERT2)23Syr mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis results in severe lesions with advanced necrosis
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis is more severe than in wild-type mice

immune system
• following treatment with tamoxifen, 2,4,6-trinitrobezene sulfonic acid (TNBS)-induced colitis is more severe than in wild-type mice





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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory