nervous system

amyloid beta deposits ( J:62290 )

• at 5 to 7 months, mice exhibit amloid beta plaques

• between 16 and 21 months, all mice develop amyloid beta plaques

neurodegeneration ( J:62290 )

• neurodegeneration is indicated by an age dependent decrease in density of synaptophysin-immunoreactive presynaptic terminals

other phenotype

amyloid beta deposits ( J:62290 )

• at 5 to 7 months, mice exhibit amloid beta plaques

• between 16 and 21 months, all mice develop amyloid beta plaques

Mouse Models of Human Disease		OMIM ID	Ref(s)
Alzheimer Disease; AD		104300	J:62290