All Phenotypes Tmem158<tm1Srn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tmem158^tm1Srn
targeted mutation 1, Manuel Serrano
MGI:3711170

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem158^tm1Srn/Tmem158^tm1Srn	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3711656

Allelic Composition	Tmem158^tm1Srn/Tmem158^tm1Srn
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem158^tm1Srn mutation (0 available); any Tmem158 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

neoplasm ( J:121067 )

• homozygous mice do not show altered susceptibility to cancer development in models of chemical carcinogenesis; papillomas in mutants are larger (but not significantly so) compared to those seen in wild-type

• fibrosarcomas generated in another model of chemical carcinogenesis occur with same latency and have same incidence as controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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