Phenotypes associated with this allele

• Allele Symbol: Akap6^tm1Jsco
• Allele Name: targeted mutation 1, John D Scott
• Allele ID: MGI:3711141
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Akap6^tm1Jsco/Akap6^tm1Jsco	involves: 129 * Black Swiss	MGI:3711660

Genotype
MGI:3711660

hm1

• Allelic Composition: Akap6^tm1Jsco/Akap6^tm1Jsco
• Genetic Background: involves: 129 * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:121227 )

• some postnatal lethality is observed; homozygous offspring are not present at expected Mendelian ratio (1:1:0.5 whereas expected ratio is 1:2:1)

growth/size/body

decreased body weight ( J:121227 )

• mice show lower body weight compared to heterozygous and wild-type littermates from birth through adulthood (~15 weeks)

craniofacial

abnormal craniofacial morphology ( J:121227 )

• some display craniofacial defects