• low auditory startle response

• disoriented

• stereociliary bundles are disorganized in all four rows of hair cells of the cochlear sensory epithelium

• often lacking clear polarity

• stereocilia are often short

• auditory threshold of more than 90 dB, indicating that lines are severely hearing impaired in 8- to 12 week old animals

• not detectable

• melanosomes fail to localize to the apical processes of retinal pigment cells

• stereociliary bundles are disorganized in all four rows of hair cells of the cochlear sensory epithelium

• often lacking clear polarity

• stereocilia are often short

• melanosomes fail to localize to the apical processes of retinal pigment cells