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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Atoh1-GFP)1Jejo
transgene insertion 1, Jane E Johnson
MGI:3703598
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Ptch1tm1Mps/Ptch1+
Tg(Atoh1-GFP)1Jejo/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 MGI:3836962


Genotype
MGI:3836962
cx1
Allelic
Composition
Ptch1tm1Mps/Ptch1+
Tg(Atoh1-GFP)1Jejo/?
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptch1tm1Mps mutation (2 available); any Ptch1 mutation (69 available)
Tg(Atoh1-GFP)1Jejo mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• 80-95% of tumor cells express GFP
• GFP+ tumor cells but not GFP- are able to propagate tumors into immunocompromised hosts

tumorigenesis
• 80-95% of tumor cells express GFP
• GFP+ tumor cells but not GFP- are able to propagate tumors into immunocompromised hosts

Mouse Models of Human Disease
OMIM ID Ref(s)
Medulloblastoma; MDB 155255 J:144811





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory