Mouse Genome Informatics
cx1
     Ptch1tm1Mps/Ptch1+
Tg(Atoh1-GFP)1Jejo/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
tumorigenesis
medulloblastoma ( J:144811 )
• 80-95% of tumor cells express GFP
• GFP+ tumor cells but not GFP- are able to propagate tumors into immunocompromised hosts

Mouse Models of Human Disease
 OMIM IDRef(s)
Medulloblastoma; MDB 155255 J:144811