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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Eloatm1Aso
targeted mutation 1, T Aso
MGI:3701319
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Eloatm1Aso/Eloatm1Aso involves: 129S/SvEv * C57BL/6 MGI:3704883
cx2
Eloatm1Aso/Eloatm1Aso
Trp53tm1Sia/Trp53tm1Sia
involves: 129S/SvEv * C57BL/6 * CBA MGI:3704887


Genotype
MGI:3704883
hm1
Allelic
Composition
Eloatm1Aso/Eloatm1Aso
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eloatm1Aso mutation (0 available); any Eloa mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• died at between 10.5 and 12.5 of gestation

embryo
• in live E10.5 embryos
• in live E10.5 embryos
• the cellularity of the spinal and cranial neuroepithelium was significantly reduced in live E10.5 embryos
• the thickness of the spinal and cranial neuroepithelium was significantly reduced in live E10.5 embryos

growth/size/body
• in live E10.5 embryos
• in live E10.5 embryos

nervous system
• the cellularity of the spinal and cranial neuroepithelium was significantly reduced in live E10.5 embryos
• the thickness of the spinal and cranial neuroepithelium was significantly reduced in live E10.5 embryos
• a poor development of the central nervous system and liver

liver/biliary system
• liver in live E10.5 embryos were markedly decreased in size and composed of irregular trabeculae with fewer hepatocytes

cardiovascular system
• in live E10.5 embryos
• showing minimum thickness of one cell layer in live E10.5 embryos

cellular
• in MEF prepared from mutant embryos
• in MEF prepared from mutant embryos
• in MEF prepared from mutant embryos

integument
• live E10.5 embryos were strikingly paler than control




Genotype
MGI:3704887
cx2
Allelic
Composition
Eloatm1Aso/Eloatm1Aso
Trp53tm1Sia/Trp53tm1Sia
Genetic
Background
involves: 129S/SvEv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eloatm1Aso mutation (0 available); any Eloa mutation (22 available)
Trp53tm1Sia mutation (10 available); any Trp53 mutation (232 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• died at between 10.5 and 12.5 of gestation
• similar to phenotype found in Tceb3tm1Aso homozygous embryos

embryo
• in live E10.5 embryos
• similar to phenotype found in Tceb3tm1Aso homozygous embryos
• in live E10.5 embryos
• morphologically not distinguishable from Tceb3tm1Aso homozygous embryos

growth/size/body
• in live E10.5 embryos
• morphologically not distinguishable from Tceb3tm1Aso homozygous embryos

cellular
• in live E10.5 embryos
• similar to phenotype found in Tceb3tm1Aso homozygous embryos





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory