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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Atp1a3tm1Ling
targeted mutation 1, Jerry B Lingrel
MGI:3696954
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Atp1a3tm1Ling/Atp1a3tm1Ling involves: 129 * Black Swiss MGI:3697484
ht2
Atp1a3tm1Ling/Atp1a3+ involves: 129 * Black Swiss MGI:3697485
ht3
Atp1a3Myk/Atp1a3tm1Ling involves: 129S1/SvImJ * C57BL/6J * C57BL/6NCr MGI:4356172


Genotype
MGI:3697484
hm1
Allelic
Composition
Atp1a3tm1Ling/Atp1a3tm1Ling
Genetic
Background
involves: 129 * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp1a3tm1Ling mutation (0 available); any Atp1a3 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• die shortly after birth




Genotype
MGI:3697485
ht2
Allelic
Composition
Atp1a3tm1Ling/Atp1a3+
Genetic
Background
involves: 129 * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp1a3tm1Ling mutation (0 available); any Atp1a3 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• increase in peak activity elicited by methamphetamine
• increased latency to find the platform in a Morris water maze
• significant increase in activity in the first 4 time intervals in an open field
• increase in peak activity elicited by methamphetamine

homeostasis/metabolism
N
• circulating levels of corticosterone, norepinephrine, dopamine, serotonin, and their metabolites are all similar to wild-type mice




Genotype
MGI:4356172
ht3
Allelic
Composition
Atp1a3Myk/Atp1a3tm1Ling
Genetic
Background
involves: 129S1/SvImJ * C57BL/6J * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp1a3Myk mutation (0 available); any Atp1a3 mutation (25 available)
Atp1a3tm1Ling mutation (0 available); any Atp1a3 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no mice were present at 4 weeks (time of death not given)





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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory