Mouse Genome Informatics
tg1
    Tg(SOD1*)125Dbo/?
involves: C3H/HeJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological
• mice develop hindlimb paralysis by 8-12 months of age

nervous system
• inclusion bodies are detected in spinal cord and brainstem
• inclusions are present at low levels in cerebral cortex and cerebellum

Mouse Models of Human Disease
OMIM IDRef(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:86421