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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(SOD1*)125Dbo
transgene insertion 125, David Borschelt
MGI:3695897
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(SOD1*)125Dbo/? involves: C3H/HeJ * C57BL/6J MGI:5056450


Genotype
MGI:5056450
tg1
Allelic
Composition
Tg(SOD1*)125Dbo/?
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice develop hindlimb paralysis by 8-12 months of age (J:86421)
• mice develop hindlimb paralysis by 8-12 months of age (J:86421)

nervous system
• inclusion bodies are detected in spinal cord and brainstem (J:86421)
• inclusions are present at low levels in cerebral cortex and cerebellum (J:86421)
• inclusion bodies are detected in spinal cord and brainstem (J:86421)
• inclusions are present at low levels in cerebral cortex and cerebellum (J:86421)

Mouse Models of Human Disease
OMIM ID Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:86421





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory