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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(SOD1*H46R*H48Q)58Dbo
transgene insertion 58, David Borschelt
MGI:3695884
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(SOD1*H46R*H48Q)58Dbo/0 involves: C3H/HeJ * C57BL/6J MGI:3833108


Genotype
MGI:3833108
tg1
Allelic
Composition
Tg(SOD1*H46R*H48Q)58Dbo/0
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• astrogliosis is observed in the cortical and hippocampal brain regions, the ventral midbrain, brain stem and spinal cord unlike in wild-type mice
• in the spinal cord of paralyzed mice

behavior/neurological
• at 4 to 6 months of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:119631





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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory