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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Olfr151tm27Mom
targeted mutation 27, Peter Mombaerts
MGI:3692987
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Olfr151tm27Mom/Olfr151tm40(Gnas*)Mom involves: 129P2/OlaHsd * C57BL/6 MGI:5788570
ht2
Olfr151tm43(Olfr151)Mom/Olfr151tm27Mom involves: 129P2/OlaHsd * C57BL/6J MGI:5788573
cn3
Gnastm5.1Lsw/Gnastm5.1Lsw
Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+
Olfr151tm28(cre)Mom/Olfr151tm27Mom
involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J MGI:5788923
cn4
Olfr151tm27Mom/Olfr151tm28(cre)Mom
Tg(CAG-Bgeo/GFP)21Lbe/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3696086


Genotype
MGI:5788570
ht1
Allelic
Composition
Olfr151tm27Mom/Olfr151tm40(Gnas*)Mom
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Olfr151tm27Mom mutation (1 available); any Olfr151 mutation (61 available)
Olfr151tm40(Gnas*)Mom mutation (1 available); any Olfr151 mutation (61 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• the RFP+ axons form compartmentalized glomeruli distinct from those formed by the GFP+ axons co-expressing constitutively active GNAS, indicating a changed axonal identity through expression of constitutively active GNAS




Genotype
MGI:5788573
ht2
Allelic
Composition
Olfr151tm43(Olfr151)Mom/Olfr151tm27Mom
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Olfr151tm27Mom mutation (1 available); any Olfr151 mutation (61 available)
Olfr151tm43(Olfr151)Mom mutation (1 available); any Olfr151 mutation (61 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• compartmentalized glomeruli are often found, with the RFP+ axons and GFP+ axons separating into separate glomeruli, indicating a change in axonal identity through doubled expression of OLFR151 levels in the GFP+ axons.




Genotype
MGI:5788923
cn3
Allelic
Composition
Gnastm5.1Lsw/Gnastm5.1Lsw
Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+
Olfr151tm28(cre)Mom/Olfr151tm27Mom
Genetic
Background
involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnastm5.1Lsw mutation (1 available); any Gnas mutation (35 available)
Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe mutation (0 available); any Gt(ROSA)26Sor mutation (745 available)
Olfr151tm27Mom mutation (1 available); any Olfr151 mutation (61 available)
Olfr151tm28(cre)Mom mutation (2 available); any Olfr151 mutation (61 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
N
• axons of OLFR151 expressing olfactory sensory neurons appear to co-converge and coalesce in glomerular formation correctly despite G-protein disruption during development




Genotype
MGI:3696086
cn4
Allelic
Composition
Olfr151tm27Mom/Olfr151tm28(cre)Mom
Tg(CAG-Bgeo/GFP)21Lbe/0
Genetic
Background
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Olfr151tm27Mom mutation (1 available); any Olfr151 mutation (61 available)
Olfr151tm28(cre)Mom mutation (2 available); any Olfr151 mutation (61 available)
Tg(CAG-Bgeo/GFP)21Lbe mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
phenotype not analyzed
• mice were used to generate permanently marked nuclear transfer ES cells and chimaeric or clonal mice





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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory