Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gbx2tm1.1(cre/ERT2)Jyhl mutation
(1 available);
any
Gbx2 mutation
(27 available)
Gbx2tm1Mrt mutation
(0 available);
any
Gbx2 mutation
(27 available)
Gt(ROSA)26Sortm1Sor mutation
(8 available);
any
Gt(ROSA)26Sor mutation
(942 available)
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nervous system
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• following tamoxifen treatment mild defects in thalamus morphology are seen in some mutants with high levels of recombination but for the most part defects in establishment of dorsal and posterior thalamic boundaries seen in null mice are not seen
• this result and chimera experiments suggest that the function of Gbx2 is cell nonautonomous
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gbx2tm1Mrt mutation
(0 available);
any
Gbx2 mutation
(27 available)
Tg(Nes-cre)1Atp mutation
(0 available)
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normal phenotype
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• mice are viable; cre expression is detected in adult brain and kidney (>99% recombination)
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