Phenotypes associated with this allele

• Allele Symbol: Map2^tm1Zhku
• Allele Name: targeted mutation 2, Z Khuchua
• Allele ID: MGI:3653757
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Map2^tm1Zhku/Map2^tm1Zhku	involves: 129X1/SvJ * C57BL/6	MGI:3654109

Genotype
MGI:3654109

hm1

• Allelic Composition: Map2^tm1Zhku/Map2^tm1Zhku
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal contextual conditioning behavior ( J:110727 )

• 2 weeks after being trained with pairing of tone and shock (CS and UCS), mutants display less freezing during the context test if placed back in the training chamber in the presence of CS/UCS; this effect is seen in 8 week old or 8 month old mice

decreased fear-related response ( J:110727 )

• mutants at 8 weeks of age show less sensitivity to shock presentations