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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Chgatm1Gnh
targeted mutation 1, Geoffrey N Hendy
MGI:3653689
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Chgatm1Gnh/Chgatm1Gnh involves: 129S1/Sv * 129X1/SvJ * BALB/c MGI:3653864


Genotype
MGI:3653864
hm1
Allelic
Composition
Chgatm1Gnh/Chgatm1Gnh
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chgatm1Gnh mutation (3 available); any Chga mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• elevated urine levels of epinephrine, norepinephrine, and dopamine
• however; renal and hepatic function are similar to wild-type

endocrine/exocrine glands
N
• gross adrenal gland morphology and microscopic structure of epinephrine and norepinephrine storing cells are similar to wild-type
• endocrine gland function and secretory function of the sympathetic nervous system, somatotrophs, and gonadotrophs are not different from wild-type

reproductive system
N
• males and females are fertile and produce normal sized litters

homeostasis/metabolism
• elevated urine levels of epinephrine, norepinephrine, and dopamine
• however; renal and hepatic function are similar to wild-type





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory