All Phenotypes Itgb1<tm1.1Efu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Itgb1^tm1.1Efu
targeted mutation 1.1, Elaine Fuchs
MGI:3639561

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itgb1^tm1.1Efu/Itgb1^tm1.1Efu	involves: 129X1/SvJ	MGI:3639578

Allelic Composition	Itgb1^tm1.1Efu/Itgb1^tm1.1Efu
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1^tm1.1Efu mutation (0 available); any Itgb1 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• at E6.5, homozygous embryos are resorbed, with only a residual population of trophoblast cells visible

embryo

absent inner cell mass ( J:108331 )

• at E6.5, embryos fail to develop an inner cell mass: embryos are identified by presence of persistent trophoblastic cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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