Phenotypes associated with this allele

• Allele Symbol: Limk2^whe
• Allele Name: white eyes
• Allele ID: MGI:3612836
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Limk2^whe/Limk2^whe	B6.Cg-Lep^ob Limk2^whe/GrsrJ	MGI:3762585

Genotype
MGI:3762585

hm1

• Allelic Composition: Limk2^whe/Limk2^whe
• Genetic Background: B6.Cg-Lep^ob Limk2^whe/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

corneal vascularization ( J:127016 )

• atypical growth of blood vessels on the cornea

increased incidence of corneal inflammation ( J:127016 )

• corneal inflammation seen by histological analysis

anterior iris synechia ( J:127016 )

corneal opacity ( J:127016 )

increased inner canthal distance ( J:223062 )

♀ • inner canthal distance is significantly larger in homozygous females

early eyelid opening ( J:127016 )

• at 2 days of age the eyelids are either completely or partially open

craniofacial

short mandible ( J:127016 )

• female, but not male, homozygotes have a shorter mandible than sex-matched heterozygous controls

immune system

increased incidence of corneal inflammation ( J:127016 )

• corneal inflammation seen by histological analysis

skeleton

skeleton phenotype ( J:127016 )

N • bone mineral density and bone mineral content are normal

short mandible ( J:127016 )

• female, but not male, homozygotes have a shorter mandible than sex-matched heterozygous controls

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:127016 )

N • ABR analysis of 2 homozygotes at 3 months of age indicates normal hearing

adipose tissue

adipose tissue phenotype ( J:127016 )

N • body composition of percent lean and percent fat are normal

cardiovascular system

corneal vascularization ( J:127016 )

• atypical growth of blood vessels on the cornea