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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(3Cd1d2-Cd1d1)1Sbp
deletion, Chr 3, Steven P Balk 1
MGI:3611776
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp either: B6NTac.129S6-Del(3Cd1d2-Cd1d1)1Sbp or (involves: 129S6/SvEvTac * C57BL/6NTac) MGI:3619518
hm2
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp involves: 129S6/SvEvTac MGI:4355893


Genotype
MGI:3619518
hm1
Allelic
Composition
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
Genetic
Background
either: B6NTac.129S6-Del(3Cd1d2-Cd1d1)1Sbp or (involves: 129S6/SvEvTac * C57BL/6NTac)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available); any Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• lack of ability to develop anterior chamber-associated immune deviation (ACAID), an example of systemic tolerance that can be elicited by introducing antigen into an immune-privileged site




Genotype
MGI:4355893
hm2
Allelic
Composition
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available); any Del(3Cd1d2-Cd1d1)1Sbp mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• Valpha14 invariant NK T cell numbers are not found in these mice
• dendritic cells loaded with alphaGal-Cer are defective in activating wild-type Valpha14 invariant NKT cells

hematopoietic system
• Valpha14 invariant NK T cell numbers are not found in these mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory