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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc7a8tm1Dgen
targeted mutation 1, Deltagen
MGI:3604565
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc7a8tm1Dgen/Slc7a8tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606655


Genotype
MGI:3606655
hm1
Allelic
Composition
Slc7a8tm1Dgen/Slc7a8tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc7a8tm1Dgen mutation (1 available); any Slc7a8 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• require an increased dose of metrazol to elicit the phase one seizure response compared to wildtype
• exhibit a decrease in motor performance on the rotarod test
• exhibit a significant decrease in total distance traveled during open field testing

nervous system
• require an increased dose of metrazol to elicit the phase one seizure response compared to wildtype





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory