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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Trpm5tm1Dgen
targeted mutation 1, Deltagen
MGI:3604455
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Trpm5tm1Dgen/Trpm5tm1Dgen B6.129P2-Trpm5tm1Dgen MGI:4418192
hm2
Trpm5tm1Dgen/Trpm5tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606671


Genotype
MGI:4418192
hm1
Allelic
Composition
Trpm5tm1Dgen/Trpm5tm1Dgen
Genetic
Background
B6.129P2-Trpm5tm1Dgen
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpm5tm1Dgen mutation (1 available); any Trpm5 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• at low concentrations, mice exhibit aversion to FeSO4 and ZnSO4 unlike wild-type mice
• at high concentrations, mice exhibit a stronger aversion to FeSO4 and ZnSO4 than wild-type mice
• mice exhibit less aversion to 10 mM CuSO4 and greater than 50 mM MgSO4 than wild-type mice




Genotype
MGI:3606671
hm2
Allelic
Composition
Trpm5tm1Dgen/Trpm5tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpm5tm1Dgen mutation (1 available); any Trpm5 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• physical examination, necropsy, histological examination of tissues and organs, bone marrow section evaluation, blood counts and differential cell counts, clinical chemistry panels, and densitometry reveal no differences from wildtype





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory