Phenotypes associated with this allele

• Allele Symbol: Twsg1^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:3604453
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Twsg1^tm1Dgen/Twsg1^tm1Dgen	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3606675

Genotype
MGI:3606675

hm1

• Allelic Composition: Twsg1^tm1Dgen/Twsg1^tm1Dgen
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body mass index ( J:101679 )

• low body weight/body length ratio trend at 49, 90, 180, and 300 days of age, which is greater in males than females

decreased body weight ( J:101679 )

• low body weight trend at 49, 90, 180, and 300 days of age, which is greater in males than females

• the magnitude of difference between wildtype and homozygotes is greatest at 300 days of age

weight loss ( J:101679 )

• body weight decreases after 180 days of age, with differences greater for males than females

decreased body length ( J:101679 )

• low body length trend at 49, 90, 180, and 300 days of age, which is greater in males than females

• the magnitude of difference between wildtype and homozygotes is greatest at 300 days of age

limbs/digits/tail

kinked tail ( J:101679 )

• 8 of 16 homozygotes display a kinked tail at 49 days of age, and 1 of 9 at 300 days of age