Phenotypes associated with this allele
Allelic Composition |
Liastm1Mae/Liastm1Mae
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Genetic Background |
either: 129S6/SvEvTac-Liastm1Mae or (involves: 129S6/SvEvTac * C57BL/6J) |
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Liastm1Mae mutation
(1 available);
any
Lias mutation
(25 available)
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mortality/aging
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• homozygous embryos die between E7.5 and E9.5
• even with lipoic acid supplementation of the dams no live born homozygotes are found
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embryo
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• embryos appear to stop growing at the egg cylinder stage
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• embryos are smaller at E7.5
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growth/size/body
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• embryos are smaller at E7.5
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Allelic Composition |
Liastm1Mae/Lias+
|
|
Genetic Background |
either: 129S6/SvEvTac-Liastm1Mae or (involves: 129S6/SvEvTac * C57BL/6J) |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Liastm1Mae mutation
(1 available);
any
Lias mutation
(25 available)
|
|
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Allelic Composition |
Liasnehe/Liastm1Mae
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Genetic Background |
involves: 129S6/SvEvTac * C57BL/6J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Liasnehe mutation
(0 available);
any
Lias mutation
(25 available)
Liastm1Mae mutation
(1 available);
any
Lias mutation
(25 available)
|
|
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embryo
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• mice exhibit anterior truncation compared with wild-type mice
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• more severe than in Liasnehe homozygotes
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growth/size/body
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• more severe than in Liasnehe homozygotes
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