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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Amelx)42Msnd
transgene insertion 42, Malcolm L Snead
MGI:3584497
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Amelx)42Msnd/Tg(Amelx)42Msnd involves: C57BL/6J * CBA/J * DBA/2J MGI:3584512


Genotype
MGI:3584512
tg1
Allelic
Composition
Tg(Amelx)42Msnd/Tg(Amelx)42Msnd
Genetic
Background
involves: C57BL/6J * CBA/J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Amelx)42Msnd mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• transmission electron microscopy of the enamel matrix of neonatal incisors reveals non-uniformity in the size of the self-assembled amelogenin nanospheres and disruption of the normally evenly-spaced, parallel arrangement of the hydroxyapatite crystallites (J:100004)
• transmission electron microscopy of the enamel matrix of neonatal incisors reveals non-uniformity in the size of the self-assembled amelogenin nanospheres and disruption of the normally evenly-spaced, parallel arrangement of the hydroxyapatite crystallites (J:100004)
• scanning electron micrographs of incisors of 6 week old mice reveal loss of the normal boundary definiton of the rods comprising the enamel and abnormal porosity of the structure formed by the rods (J:100004)
• scanning electron micrographs of incisors of 6 week old mice reveal loss of the normal boundary definiton of the rods comprising the enamel and abnormal porosity of the structure formed by the rods (J:100004)

growth/size/body
• transmission electron microscopy of the enamel matrix of neonatal incisors reveals non-uniformity in the size of the self-assembled amelogenin nanospheres and disruption of the normally evenly-spaced, parallel arrangement of the hydroxyapatite crystallites (J:100004)
• transmission electron microscopy of the enamel matrix of neonatal incisors reveals non-uniformity in the size of the self-assembled amelogenin nanospheres and disruption of the normally evenly-spaced, parallel arrangement of the hydroxyapatite crystallites (J:100004)
• scanning electron micrographs of incisors of 6 week old mice reveal loss of the normal boundary definiton of the rods comprising the enamel and abnormal porosity of the structure formed by the rods (J:100004)
• scanning electron micrographs of incisors of 6 week old mice reveal loss of the normal boundary definiton of the rods comprising the enamel and abnormal porosity of the structure formed by the rods (J:100004)

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Amelogenesis Imperfecta, Type IE; AI1E 301200 J:100004





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory