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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ntrk3tm1Ddg
targeted mutation 1, David D Ginty
MGI:3583736
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ntrk3tm1Ddg/Ntrk3tm1Ddg involves: 129P2/OlaHsd * C57BL/6 MGI:3584419


Genotype
MGI:3584419
hm1
Allelic
Composition		 Ntrk3tm1Ddg/Ntrk3tm1Ddg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk3tm1Ddg mutation (1 available); any Ntrk3 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:99603 )
• viable and fertile, with no obvious behavioral abnormalities, however NMPP1, a derivative of the general kinase inhibitor PP1, inhibits neurotrophin signaling in neurons unlike in wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory